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Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

In the present study, the serum or gastric pro-inflammatory cytokines TNF- and IL-1 as well as the mRNA expression of NF-B were reduced by NPW treatment in the rat gastric tissue, indicating the anti-inflammatory action of NPW against acetic acid-induced gastric injury also occurs through the suppression of NF-B pathway

In particular, the therapeutic principle of acupuncture still needs to be explored in depth, and the accompanied therapeutic mechanism and application potential of traditional Chinese medicine in depression deserve to be explored in depth

These data also demonstrate the effectiveness of inactivating CHAC1 as a novel strategy to preserve muscle glutathione

The mechanism of neural precursor cell expressed developmentally down-regulated 4-2 (Nedd4-2)/NEDD4L-catalyzed polyubiquitin chain assembly