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Keywords Alzheimer's disease Adult zebrafish Aluminium chloride Okadaic acid Litsea garciae Acute toxicity AD Alzheimer's disease AlCl 3 Aluminium chloride OKA okadaic acid NTT Novel tank test LG Litsea garciae CREAM Central Research and Animals Facility IACUC-IIUM Institutional Animal Care & Use Committee IIUM SBC Sarawak Biodiversity Centre OECD Organisation for Economic Cooperation and Development LC 50 lethal concentration pH potential of hydrogen Abbreviations Introduction Alzheimer's disease (AD) can have secondary effects on anxiety and locomotion in addition to its primary impact on cognitive functions such as memory, thinking, and reasoning

These enzymes catalyze the formation of key regulators of calcium signaling, namely (linear) ADP-ribose, cyclic ADP-ribose, and nicotinic acid adenine dinucleotide phosphate ( Figure 5 )

285 Overexpression of miR-196a downregulates both mRNA and protein levels of HOXC8, a predicted target of miR-196a

doi: 10.1007/s12035-025-05137-4 233 ScheltensP.De StrooperB.KivipeltoM.HolstegeH.ChetelatG.TeunissenC

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What regulatory status applies to these peptides across regions