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Previous studies established that CAT inhibits ferroptosis by activating transient receptor potential vanilloid type 1 (TRPV1), thereby upregulating GPX4 expression and ameliorating intestinal ischemiareperfusion injury as well as organoid hypoxia-reoxygenation injury (Deng et al., 2021)

Vo TTT, Peng TY, Nguyen TH, Bui TNH, Wang CS, Lee WJ et al (2024) The crosstalk between copper-induced oxidative stress and cuproptosis: a novel potential anticancer paradigm