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Koizumi T, Kerkhofs D, Mizuno T, et al

In a randomized, placebo-controlled phase 1 clinical trial, 14-day treatment with TLC-2716 was well tolerated (primary endpoints) and resulted in placebo-adjusted reductions up to 38.5% in plasma TG and 61% in postprandial remnant cholesterol (secondary endpoints)

Healthy female mice served as pure controls

[DOI] [PubMed] [Google Scholar] 71.Heisterkamp N., Groffen J., Warburton D., Sneddon T.P

doi: 10.1016/j.pneurobio.2020.101890 62 StockwellBRFriedmann AngeliJPBayirHBushAIConradMDixonSJet al