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942,943,944 It also increases cancer cell sensitivity to chemotherapy by impeding GLUTs

Given that the rs13107325 (p.Ala391Thr) variant has been linked to 22 clinical phenotypes 44,313 , an important question is whether this pleiotropy reflects the diverse roles of Mn as an enzymatic cofactor or a common downstream signaling mechanism

While formal clinical trials are limited, anecdotal reports suggest that glycine-enhanced formulations may help users experience deeper rest and better nighttime hormone release