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Also under these conditions, RPE migrates towards hyperglycemic areas

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Glutathione and Cysteine: Glutathione is a low-molecular-weight thiol-tripeptide, primal to the maintenance of intracellular redox balance: it is an antioxidant present in almost every cell in the body, playing a role in the detoxification of xenobiotics, drugs and pollutants

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However, during inflammatory condition where there is a high demand to consume NADPH, G6PD is released from its inhibition and forms an active homodimer (51, 52)

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The pathway from subcutaneous injection to systemic circulation is straightforward: interstitial diffusion capillary uptake venous return cardiac output arterial distribution

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The monitoring of GSH/GSSG ratio and the quantification of GSSG in biological samples are essential for evaluating the redox and detoxification status of cells and tissues in relation to the protective role of glutathione against oxidative and free-radical-mediated cell injury

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