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Description

Furthermore, conditioned medium of bovine aortic endothelial cells enhanced vascular smooth muscle Na/K pump activity to a far greater degree in spontaneously hypertensive rats than normotensive controls, with the effect reduced following treatment with PKC inhibitor staurosporine, pointing to a role for PKC in enhanced endothelium-dependent microvascular responses in hypertension (143)

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The AHR is a ligand-dependent transcription factor expressed by epithelial cells, immune cells, microglia, and astrocytes

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