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Sheu RK, Pardeshi MS

These pathways are typically assessed using phosphorylation assays, metabolic flux analysis, and gene expression profiling in adipose and related tissues

446 Interestingly, a post-hoc analysis indicated that baseline serum lactate dehydrogenase (LDH) levels could be a potential predictive factor for treatment response

Another theory suggests that activation of microglia leads to the release of pro-inflammatory molecules, an increase in oxidative stress, and mitochondrial dysfunction within microglia