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The BAY-876/V-9302@HSA nanoparticles were spherical in shape (Fig

To overcome these constraints, Plasmodium parasites increase the permeability of the erythrocyte membrane to isoleucine and other low-molecular-weight solutes it requires for growth by forming new permeation pathways (NPPs)

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Through these mechanisms, mitochondrial activity can exert rapid effects via histone modifications or longer-term effects through DNA methylation

Specifically, the authors found that acute glycolytic inhibition increased glutathione and pyruvate metabolism

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