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Such mechanisms are particularly relevant to PCOS, where systemic oxidative stress, hyperinsulinemia, and androgen excess establish a pre-activated metabolic state that lowers the threshold for both NOX2- and mitochondria-dependent NET formation (61)

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It plays a crucial role in detoxifying the body, protecting cells from oxidative stress, and supporting immune function

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It is believed to have had up to 4,000 inhabitants