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Palmer BF (2002) Renal dysfunction complicating the treatment of hypertension

10.1186/s13690-023-01148-6 129

35 JiangY.DongG.SongY

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To study the contribution of specific MDA-binding IgM antibodies to ALD, wildtype mice were injected with LR04 antibodies or isotype control IgM during chronic-binge ethanol feeding

These include regulation of mechanisms controlling reactive oxygen species (ROS), which cause macromolecular damage 16,17 , mitochondrial turnover or mitophagy 18 , and the mitochondrial unfolded protein response (UPR mt ), in which mitochondrial damage can be prevented by the removal of aggregated or unfolded proteins 19