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In addition, this bilayer structure entraps a small quantity of water in the center of the structure: it is in this aqueous core that hydrophilic compounds such as vitamin C can solubilize and are transported

This reaction oxidizes dihydrolipoamide (Lip(SH)2) that is the catalytic moiety of dihydrolipoyl transsuccinylase (E2), the second enzyme of the complex

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Interestingly, although GSH treatment alone also invoked some gene expression changes, GSH supplements dampened most of the bortezomib-induced gene expression changes (Figure 2a)

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Mitophagy is the process by which damaged or dysfunctional mitochondria are selectively removed via autophagy