glutathione study Glutathione and Vitamin C supplement

Early study initially suggested that disruptions of the insulin or GH/IGF1 axis with low insulin and IGF1 levels may enhance autophagy to prevent the age-related mitochondrial degradation and extend the lifespan (Wang and Miller (2012) demonstrated that fibroblasts in Snell mice (which secrete very low amounts of GH, prolactin, and thyroid-stimulating hormone) are more susceptible to autophagy induced by amino acid withdrawal or by oxidative stress than control cells

10.1074/jbc.M117.792838 J

Were going to put two cross pins across the tib fib so they get close enough

10.1017/s095026881000052x 21 EndoH.HigurashiT.HosonoK.SakaiE.SekinoY.IidaH.et al (2011)

A baseline level of oxidative stress is a normal stimulus for muscular adaptation

Cell culture systems do not replicate the complexity of whole-organism biology