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Associated changes of lipid peroxidation and transforming growth factor beta1 levels in human colon cancer during tumor progression

10.1177/0960327113499167 Hum Exp Toxicol

TRPM2-deficient microglia exhibited increased LC3A/B-II levels, indicative of autophagosome formation, and decreased SQSTM1/p62 levels, suggesting enhanced autophagic flux

doi: 10.1016/j.phymed.2024.155815 51 SunJMLiuYXLiuYDHoCKTsaiYTWenDSet al

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Activated LINE elements generate abundant RNADNA hybrids, which are recognized as foreign nucleic acid signals by the cGAS-STING pathway, inducing immune responses and amplifying inflammatory signals closely linked to neuroinflammation in AD