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doi:10.1038/nature08299

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That is a coincidence of separate experiments, not a measured result

MK-677 is a first-in-class ghrelin mimetic that increases both GH and IGF-1 levels without altering cortisol or testosterone, offering anabolic potential with minimal endocrine disruption. Murphy et al., Nature Reviews Drug Discovery How Does MK-677 Work

Under physiological conditions, it supports synaptic plasticity [346], whereas under pathological states, such as during astrocytic necroptosis, proBDNF may exert neurotoxic effects and promote apoptotic signaling [349]

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