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Mechanistically, EDCs can act as agonists or antagonists at estrogen receptors (ER and ER), androgen receptors (ARs), or thyroid hormone receptors (TRs), thereby altering receptor conformation, recruitment of coactivators or corepressors, and downstream transcriptional activity [72,73]

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NLRX1 attenuates apoptosis and inflammatory responses in myocardial ischemia by inhibiting MAVS-dependent NLRP3 inflammasome activation

Restricting cysteine, depleting GSH, or inhibiting GPX4 can increase phospholipid peroxidation in responsive cells, but sensitivity also depends on lipid composition, iron metabolism, parallel antioxidant systems, and tissue context (Jiang et al., 2021)

It's just not enough time

The BMI of patients with deep infiltrating endometriosis was the lowest (23.24.5) and those with adenomyosis only was the highest (27.56.3)