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ERK, Extracellular signal-regulated kinase

conducted a pilot study and found that tcVNS can effectively improve gait abnormalities in PD, especially in terms of gait time and stride length (122)

model 3: OR = 0.73, 95% CI = 0.540.98

However, because more IGF1 LR3 remains free and available for receptor interaction, it shows greatly greater potency in research uses, often producing equivalent effects at doses 10-100 times lower than those needed for native IGF-1