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iDC expresses two active histamine receptors, H1 and H2, and stimulation by LPS and simultaneous administration of exogenous histamine can act on H2 receptors for a short period of time, increasing IL-10 production and decreasing IL-12 secretion, and ultimately polarizing CD4 + T cells to a Th2 phenotype (100)

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The energetically best cluster complex structure was next used for refinement and dynamic analysis

doi: 13 10.1016/j.mri.2016.1307.1016

Our proposed system overcomes the difficulties associated with the topical administration of copper peptides and achieves efficient delivery in a localized and non-invasive manner

J Nanobiotechnology 21(1):214