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Table 1 Genetic mutations identified in familial and sporadic forms of amyotrophic lateral sclerosis (ALS)

doi: 10.1038/s41467-017-01567-4 188 ChooAYKimSGVander HeidenMGMahoneySJVuHYoonSOet al

AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence

The relative expression levels of the selected DEPs normalized to the expression level of the internal reference control were calculated using the 2 -Ct method

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3.5 Integrated and synergistic network of action In the intestinal ecosystem, probiotic mechanisms function as an integrated, synergistic network rather than as isolated processes