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Understanding the full landscape of how long tirzepatide takes to work and how long appetite suppression takes to develop helps frame realistic maintenance expectations

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semaglutide Month 13: Faster initial fat loss, avg 23 lbs/week Month 36: Significant body composition improvement 7288 weeks: Average 2025% total body weight reduction SURMOUNT-5: Tirzepatide confirmed superior to semaglutide head-to-head (2025)

In some cases, health insurance companies may partially or fully cover the cost of the medicine

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