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Cell culture and measurement of cellular NAD + CHO cells stably transfected with a mouse CD38 plasmid (CHO-mCD38) were cultured in DMEM medium supplemented with 10% FBS (Thermo Fisher Scientific), 2 mM L-glutamine, 120 U ml 1 penicillin and streptomycin (Lonza, Alpharetta, GA), and 400 nM nicotinamide mononucleotide (NMN))

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When Crohns affects the upper small intestine and stomach, it can also cause complications in the esophagus or mouth

Many patients also report lingering pain and reduced shoulder function even after surgery