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10.1016/j.ejps.2018.02.032 67

The ETC defects observed in Alzheimers disease (AD), PD and MSA have been attributed to somatic mitochondrial (mt) DNA mutations 28,29 where high levels of mtDNA deletion or depletion affect the activity as well as the subunit expression of mtDNA encoded ETC complex subunits (complex I, III, IV and V) 30

In addition, a significant decrease in the levels of miR-29 has been found in lesional SSc skin [23]

Lack of effect of oral sulforaphane administration on NRF2 expression in COPD: a randomized, double-blind, placebo-controlled trial

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