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We performed scRNA-seq using a mouse CRC liver metastasis model with mouse CRC MC38 cells

The mechanism is as follows, RXR binding and heterodimerization with PPAR bound to fatty acids, eicosanoids, and several synthetic ligands, carotenoids influence immunological responses [78]

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As VD 3 is the form produced in the human skin, it is thus not surprising that only VD 3 is significantly lower in adults compared to children