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This idea sounds appealingbut its not well supported by existing evidence

Mitrovic, I., Lu, Y

Weight reduction alone does not reverse central sensitization, the core mechanism of fibromyalgia, making GLP-1 therapy insufficient as a primary pain management strategy

When discussing how long peptides stay in the system, two terms are particularly important: half-life and detection time: WORTH NOTING: Natural peptides typically have short half-lives, often just minutes to an hour, due to rapid enzymatic degradation, while synthetic peptides can be designed to last longer, with half-lives ranging from hours to several days