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Results from this study suggest that increased levels of MMA and Hcy in seniors are brought about by a reduced renal function due to aging rather than by an underlying vitamin B 12 insufficiency (Risch et al., 2015)

Mitochondria and xanthine oxidase both generate reactive oxygen species in isolated perfused rat liver after hypoxic injury

10.1161/01.ATV.20.4.989 180

Our results showed that there are impacts of early exposure on methylation patterns and that these patterns can vary with the second exposure, supporting our hypothesis and providing evidence for molecular carryover effects

in this case, all individuals (or majority) living in a given area are exposed to iodine excess