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Theres limited scientific evidence directly linking semaglutide use to vitamin B12 deficiency or recommending routine vitamin B12 supplementation for people taking semaglutide

Treatment recommendations are based on medical evaluation, clinical appropriateness, and provider judgment

Stem Cell Rev Rep 18:18091821 Rosrio C, Zandman-Goddard G, Meyron-Holtz EG, DCruz DP, Shoenfeld Y (2013) The hyperferritinemic syndrome: macrophage activation syndrome, Stills disease, septic shock and catastrophic antiphospholipid syndrome

In the US, they are also licensed for use in young people aged 12 or older who weigh at least 35kg

While some peptides are known to be stable when mixed, this introduces another variable

Do not use syringes larger than 1mL for the actual injection, as the larger barrel makes precise measurements difficult