Furthermore, studies investigating TCM treatments for depression based on the ferroptosis framework are scarce, primarily focusing on depressive animal models, with a lack of supportive clinical trial results
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Alternatively, the increased longevity could have resulted from decreased product-inhibition of the nematode homolog of cytoplasmic GPD1 by decreasing glycerol-3-phosphate levels, leading to increased flux through GPD1 to oxidize the cytoplasmic [NAD + ]/[NADH], a known prolongevity intervention (Lautrup et al., 2024)
esto lo hace preferible en estudios que buscan reproducir la secrecin pulstil fisiolgica