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Given the central role of ROS homeostasis in health and disease, targeting ROS and their mediated ROS balancing pathways holds great therapeutic potential [556, 557]

[Abstract]2024 Jun 8:74:103225

Thus, 53.8 million pregnant women worldwide suffer from vitamin A deficiency (VAD) and anaemia, two prevalent micronutrient deficiencies

The duration of the chemotherapy treatment is another possible risk factor for CIPN

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Under stress such as amino acid deprivation or oxidative condition, NRF2 migrates to the nucleus to initiate transcription of the antioxidant response element (ARE)-containing genes via disassociation from KEAP1 [78]