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The combination of the CD38 mAb with an IMiD remarkably enhances NK cell-mediated ADCC by increasing the quantity and activity of NK cells, promoting the tumoricidal activity of macrophages, and enhancing CD38 mAb-mediated ADCP

Graber JJ, Sherman FT, Kaufmann H, Kolodny EH, Sathe S

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Blocking experiments confirmed the CD38 specificity of tumor uptake by CD3813

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