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10.1093/hmg/ddu409 Summary Keywords amyotrophic lateral sclerosis (ALS), TDP-43, mitotoxicity, liquid-liquid phase separation (LLPS), endocytosis, frontotemporal lobar degeneration (FTLD), prion, ALS therapeutics Citation Prasad A, Bharathi V, Sivalingam V, Girdhar A and Patel BK (2019) Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis

In unchallenged cells, mTORC1 phosphorylates directly GRASP55 at the Golgi to retain its subcellular localization

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Several publications report silver to be non-toxic, with argyria, a rare and irreversible pigmentation of the skin caused by silver deposition, as the only reported side-effect (6, 18)