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Therefore, these nanoparticles integrate tumor-selective activation, multi-modal cell-killing, microenvironment modulation, and immune potentiation into a single programmable platform, which suppresses primary and metastatic tumors sustainably with the minimum systemic toxicity

Professors Miyuki Hino and Antonia Sebastian

doi: 10.14639/0392-100X-N0311 76 MenzABauerRKluthMMarie von BargenCGorbokonNViehwegerFet al

Clarifying the difference of metabolic profiles and of molecular mechanisms between HFrEF and HFpEF might provide clinical significance of carnitine metabolism as new therapeutic target for metabolic disorder in hypertensive HFpEF, remaining unmet medical needs in cardiovascular medicine