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NTS treated with TRFS-Green only were clearly fluorescent after 2 h incubation (Fig

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The results showed both genotypes shared enrichment in metabolic pathways, phenylpropanoid biosynthesis, and glutathione metabolism though the extent and significance of gene enrichment varied (Fig

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As we seek to develop more potent PINK1 inhibitors based on these scaffolds, the challenge will be to reduce the potency against other kinases to achieve sufficient selectivity for their use as chemical probes