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Additionally, the antioxidant melatonin has been demonstrated to increase ATP levels in the oocytes of older mice (12 months old), reduce cellular apoptosis and DNA damage, prevent spindle and chromosomal abnormalities, and improve intercellular communication between oocytes and ovarian somatic cells

[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Jozefczak M., Remans T., Vangronsveld J., Cuypers A

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