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Nature 580 , 530535 (2020)

Gastroenterology, 134(1), 166-178

\Anti-inflammatory Effects: May reduce oxidative stress and inflammatory cytokines (Animal Study)

In addition, kidney weight was markedly reduced in GH-treated and untreated JAK2 -/- mice compared to controls, indicating the importance of circulating IGF-1 in kidney growth, whereas locally produced IGF-1 seems not to have a significant impact on kidney growth