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At day 21, cells were cultured in proliferative medium under different conditions for 72 h: (i) basal control conditions, and (ii) treatment with FM19G11-loaded NPs (500 nM FM19G11)

Establishment of cisplatin-induced AKI mouse model Idh1 WT/WT Ksp Cre mice and IDH1-R132H mutant ( Idh1 WT/Mut )Ksp Cre mice were housed in a pathogen-free environment and randomly divided into the following groups ( n = 6 per group): control group, cisplatin group, cisplatin + Liproxstatin-1 (Lip-1) group, and cisplatin + benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone (zVAD) group

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The injectate should proceed without any resistive pressure and often an expansion of fluid can be seen anterolaterally consistent with inflation of the bursa