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In the obesity group, there was a significant and clinically meaningful reduction in body weight of 4.74% at week 8, with weight continuously decreasing during the 8-week treatment period

They have received approval from the U.S

DSIP was less potent than GnRH and as potent as TRH in inducing LH and TSH differentiation

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Snyder MC, Johnson PJ, Moore GF, Ogren FP

Dose-Response Relationships In animal stroke models, gene expression changes occurred 1-24 hours post-administration, but whether similar timing applies to psychiatric effects is unknown