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doi: 10.1038/s41598-022-11236-2 Summary Keywords metformin, rectal cancer, colorectal, radiosensitiser, energy metabolism, radioresistance Citation Buckley CE, OBrien RM, Nugent TS, Donlon NE, OConnell F, Reynolds JV, Hafeez A, ORordin DS, Hannon RA, Neary P, Kalbassi R, Mehigan BJ, McCormick PH, Dunne C, Kelly ME, Larkin JO, OSullivan J and Lynam-Lennon N (2023) Metformin is a metabolic modulator and radiosensitiser in rectal cancer

We also analyzed the levels of aspartate transaminase (AST) and alanine transaminase (ALT) after hepatocyte injury

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Although rips-1 was not found in the study, we reasoned that due to the regulation of its paralogues by H 2 S and the similarities in DTT, -mercaptoethanol, and H 2 S, rips-1 may also respond to H 2 S

However, it has the limitation of not simulating clinical chronic wound bacterial biofilms