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The results from 10 consecutive Pareto-efficient frontiers for each condition are listed in the appropriate groupsfemale, male, control, or diseaseand then compared using a Venn diagram to identify common gene solutions (see Table S2)

The MS was operated using the LC-MS/MS system (SCIEX 6500, MA, United States) in positive mode

GSH, released by astrocytes, undergoes a cleavage process by -glutamyl transpeptidase (GT) [29] producing a -glutamyl moiety and a dipeptide CysGly which is an essential precursor of neuronal glutathione