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PARP1-catalyzed PARylation of YY1 mediates endoplasmic reticulum stress in granulosa cells to determine primordial follicle activation

A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles

Its a holistic approach that many find aligns well with their health goals

[DOI] [PubMed] [Google Scholar] 104.Cai Y.-J., Wang F., Chen Z.-X., Li L., Fan H., Wu Z.-B., Ge J.-F., Hu W., Wang Q.-N., Zhu D.-F

We first provide a brief background on the multi-target cardiovascular effects of TCM-derived metabolites (Figure 1), then discuss evidence for their benefits in specific disease contexts (atherosclerosis, hypertension, myocardial infarction, heart failure), integrate findings from clinical studies, and finally consider the challenges and future directions for translating these therapies into mainstream cardiovascular care

You know, that's the other thing that you hear