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Inclusion criteria consisted of male and female participants without child bearing ability either due to menopause, documented hysterectomy, bilateral salpingectomy, bilateral oophorectomy, or bilateral tubal ligation, as well as age of at least 18 years, a body mass index of 30, or a body mass index of 27 with the presence of hypertension or dyslipidemia [1]

It is under investigation in preclinical and clinical studies on overweight, obesity, and metabolic disorders, where researchers have examined its effects on body weight and energy intake, including when combined with GLP 1 receptor agonists such as semaglutide, but it is not an approved therapy

Tirzepatide: What the Human Evidence Actually Shows Tirzepatides evidence base is the kind that supports an approval: large, completed, randomised Phase 3 trials with active and placebo comparators

The primary endpoint was the percentage change in body weight from baseline to week 26

Short-term storage: Room temperature in a sealed container is acceptable for several months

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