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AOD-9604 Research Applications & Key Findings Metabolic and Obesity Research Weight Loss and Fat Reduction Studies Initial clinical trials in obese adults showed promising results, though later studies revealed limitations

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NMNAT isoforms play fundamental roles in early development as well as in preserving neuronal integrity and protecting against neurodegeneration [95]

Reported weekly weight-loss differences over placebo were small (in the range of -0.06 to -0.15 kg/week, depending on dose)

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It is overexpressed in the adipose tissue of obese and diabetic individuals