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The peptide appears to shift macrophage polarization from pro-inflammatory M1 phenotypes toward anti-inflammatory M2 phenotypes, thereby facilitating tissue repair and regeneration

It is speculated that Fra-2 may be a potential therapeutic target for pulmonary fibrosis (275)

(Description of peptide stability and experimental results in an animal model)

Some plant-based foods, however, are fortified with B12, including nutritional yeast, breakfast cereals, and plant milks

doi: 10.3389/fimmu.2020.570195 212 LiuYAliHKhanFPangLChenP

It is used not only in fortified foods but also in dietary supplements 1,34,98,139,222,579,580,581,582,583,584,585,586,587,588,589,590,591,592,593,594,595,596,597,598,599,600,601,602,603,604,605,606,607,608,609,610,611,612