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People who eat a vegan diet and do not take vitamin B12 supplements or eat foods fortified with vitamin B12, are also at risk

10.1038/cddis.2014.155 Cell Death Dis

doi: 10.1111/j.1365-3040.2010.02222.x 68 ReczekC

doi:10.1002/jcp.26249 Tabeshpour J, Hashemzaei M, Sahebkar A

Figure 1 1.3 Neuroimmune axis: crucial mediator of ENS regulation in colitis The ENS critically regulates intestinal inflammation through bidirectional interactions with immune circuits, collectively forming the neuroimmune axis ( 2+ flux, suppresses macrophage activation, and limits pro-inflammatory cytokine release ( Salmonella -induced colitis preferentially damages glutamatergic myenteric neurons expressing certain atypical inflammasomes

Recently, a new L-asp GRASPA wrapped in red blood cells provides better safety and seems to have better efficacy for elderly patients with leukemia