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Previous research has reported that RGS4 overexpression suppresses the proliferation of human breast cancer cells by proteasome degradation (33)

Exposure of immature mouse oocytes at the germinal vesicle stage (GV oocytes) to H 2 O 2 increases levels of reactive aldehydes, including 4-hydroxynonenal (4-HNE), which modifies and damages -, -, and -tubulins, essential for spindle assembly

The result is that tag is not accessible to coordinate with the metal, typically nickel or cobalt

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