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Another explanation is that L-aspartyl-4-P is possibly an inducer of the sulfate reduction pathway or otherwise regulates sulfate reduction such that the loss of HOM3 results in a decrease in the pathway activity and compensates for the loss of reduced sulfide incorporation

Adv Radiat Oncol 5(3):369-376, 2020

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The main feature of neuroinflammation is the activation of microglia, which releases neurotoxic substances and pro-inflammatory cytokines, resulting in the death of neurons

In addition, kidney-resident immune cells may have a surveillance or regulatory role in the kidney but can accumulate in response to injury