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In summary, IV ketamine generally provides the highest efficacy due to its complete bioavailability and rapid onset, followed by IM injections, while ketamine lozenges offer significantly lower bioavailability but greater convenience

The UK and USA are however recommending the following regimen 100 mg/kg IV over 30 minutes (maximum of 6 grams) followed by maintenance doses of 15 mg/kg every 4 hours

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For example, precise WUS expression patterns require chromatin regulators, and mutants of these factors display bigger and disorganized meristems (Graf et al

6c).To further prove whether ferroptosis is involved, we conducted cell viability assays by using CCK-8