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Consequently, the slow-releasing H 2 S donors, such as GYY4137 and dithiolthione compounds, offer an attractive alternative, providing controlled release and sustained H 2 S bioavailability that more closely mimics endogenous production rates, thereby reducing the risk of bolus effects (Giustarini et al., 2010

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Researchers frequently use mushroom tyrosinase (mTYR) to evaluate the inhibition capabilities of compounds, but the structural differences between hTYR and mTYR present considerable challenges in accurately developing hTYR-specific inhibitors

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Early astrocytic dysfunction is associated with mistuned synapses as well as anxiety and depressive-like behavior in the AppNL-F mouse model of Alzheimers disease

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