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However, even at a high concentration (50 M), it could not induce apoptosis or cause the activation of aspases-3, -8 and -9

Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity

After cooling, the resulting white crystals were filtered off and washed with acetone followed by drying in vacuo to yield 5.3 g [47%, m.p

Malondialdehyde (MDA) is a highly reactive and toxic by-product of lipid peroxide degradation and is therefore used as a surrogate marker for lipid peroxidation

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