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This has clinical relevance, as both insulin and free IGF-1 levels are increased in individuals with obesity, and T cells have been found to dominate peripheral inflammation in obesity in human studies, with Th17 cells having a particularly prominent role 30,31,32

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Vitamin B6 supports the protective coverings on nerve endings, but it should be taken cautiously, as excessive doses can contribute to further nerve damage

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Physicians typically evaluate body composition changes, any side effects, and metabolic markers before continuing or adjusting protocols

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