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Description

Steele, B.K

However, it will be essential to further elucidate the precise signalling pathways and mechanisms in which ROS is involved in wound healing

These findings may have general implications in the use of total (free + conjugated) oxidative metabolite excretion for determining primary routes of drug clearance and may question the utility of diclofenac as a probe for phenotyping human CYP2C9 activity in vivo via measurement of its pharmacokinetics and total 4'-hydroxy diclofenac urinary excretion

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